Metallothioneins and related chelators by astrid sigel, 9781847558992, available at book depository with free delivery worldwide. To determine whether all four types of plant mts function as metal chelators, six arabidopsis arabidopsis thaliana mts. Chelating agents and metal chelates 1st edition elsevier. Chelating agents of a new generation as an alternative to conventional chelators for heavy metal ions removal from. Preface to volume 5 metallothioneins and related chelators metallothioneins are cysteinerich low molecular mass 5 to 10 kda proteins, occurring from bacteria to humans, having, in the case of vertebrates, commonly 7 metal ions incorporated.
Chelation is a type of bonding of ions and molecules to metal ions. Chelating agents are capable of binding to toxic metal ions to form. Metallothioneins and related chelators metal ions in life sciences by astrid sigel editor helmut sigel editor. These sulfurrich chelators, being important in metal ion homeostasis, find increasing attention. Find a library or download libby an app by overdrive. This title is not available to purchase from royal society of chemistry. For a complex with i ligands not associated in one molecule, the change in enthalpy related to bonding often contributes considerably to the free energy because. Molecules and ions with free electron pairs tend to form complexes whose. Metallothioneins and related chelators volume 5 metal. Power point presentation on how metallothionein removes toxic metals and improves some cases of alzheimers disease. Metallothioneins and related chelators rsc publishing. Toxicity of free iron is mediated by the free radicals. In vitro evidence for the isoformspecific partitioning of cadmium and zinc ions between the two c. Metal chelators are emerging as versatile tool with many medical applications.
Molecular mechanisms of in vivo metal chelation ncbi nih. Use of chelating agents to extract heavy metals from contaminated soils is seen as. Prices in gbp apply to orders placed in great britain only. An equilibrium constant, k, is related to the standard gibbs free energy. Mils5, written by 30 internationally recognized experts, focuses on this hot topic. Their versatility allows them to be used in chelation therapy for. The reader is supported by about 20 tables, more than 80 illustrations and nearly 2000 references. Juan hidalgo, roger chung, milena penkowa and milan vasak. However, due to transit disruptions in some geographies, deliveries may be delayed. Chelating agents of a new generation as an alternative to. Prices in represent the retail prices valid in germany unless otherwise indicated.
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